Kafukufuku waposachedwa wapakatikati pa matenda a matenda a cryptococcal adachitidwa ndi Medical Center ya Utrecht University, Institute of Biodiversity and Ecosystem Dynamics ya University of Amsterdam, Westerdijk Institute for Fungal Biodiversity, ndi Matogro The Fungi Research Laboratory of the Federal University of Somalia ndi Júlio Muller University Hospital of the Federal University of Mato Grosso pamodzi anayambitsa ndi kufalitsa mutu wakuti "Kunyalanyaza chibadwa cha majini" mu Journal of Clinical Microbiology mu January 2021. Zosiyanasiyana zimalepheretsa kuzindikiritsa matenda a Cryptococcus panthawi yake.Nkhaniyi ikufanizira zinthu zinayi za cryptococcal colloidal golide zozindikira, ndikuwunika momwe chida chilichonse chimagwirira ntchito pamitundu yosiyanasiyana ya cryptococcal malinga ndi momwe Cryptococcus neoformans ndi Cryptococcus guttata.Perekani maziko othandiza pakuzindikira mwachangu kwa Cryptococcus.
Mitundu inayi ya ma cryptococcal colloidal gold quick test reagents anagwiritsidwa ntchito kuyesa mitundu yosiyanasiyana yowonetsa mitundu yosiyanasiyana ya ma cryptococcus, kuphatikiza zopangidwa ndi makampani anayi ndi mitundu kuphatikiza Tianjin FungiXpert® ndi IMMY Diagnostics ya United States.Mitundu makumi anayi ya Cryptococcus kuphatikiza mitundu isanu ndi iwiri yodziwika bwino ndi ma hybrids awo osakanikirana adayesedwa.
Zotsatira za kafukufuku:
Zotsatira za kafukufuku zikuwonetsa kuti FungiXpert® (mtundu wa Genobio) ndi IMMY's colloidal gold test card can find all seven pathogenic Cryptococcus.
Poyesa zinthu zina ziwiri za golidi wa colloidal, mitundu ina monga C. bacillisporus, C. deuterogattii, ndi C. tetragattii, makamaka C. tetragattii, imakhala ndi zotsatira zolakwika zabodza.Komabe, matenda a C. tetragattii ali ofala ku sub-Saharan Africa ndi Indian subcontinent, omwe ali ndi chiwerengero chachikulu cha matenda okhudzana ndi HIV okhudzana ndi kachilombo ka cryptococcal meningitis.Chofunika kwambiri, 13-20% ya matenda a cryptococcal meningitis okhudzana ndi HIV amakhudzana ndi C. tetragattii.
Poona malipoti aposachedwa a zotsatira zabodza za mayeso a cryptococcal ku Botswana ndi Uganda, olembawo adatsimikiza kuti C. tetragattii akuyenera kukhalapo muzofufuza zachipatala ndi zotsatira zolakwika izi.
Mapeto a kusanthula:
Wolembayo akuwonetsa kuti pakukhazikitsa kapena kuunika kwa njira zodziwira za cryptococcal, miliri ya m'deralo, ma genetic ndi mitundu yosiyanasiyana ya taxonomic iyenera kuganiziridwa.Cryptococcus pathogenic sayenera kungokhala gulu limodzi la AD serotypes.Poganizira njira yosinthidwanso ya cryptococcal pakupanga ndi kutsimikizira kungachepetse kutayika kwa chidwi komwe kumachitika chifukwa cha zolakwika zabodza.
Khadi lodziwikiratu la cryptococcal capsular polysaccharide (njira ya golide ya colloidal) yopangidwa ndi kupangidwa ndi Genobio Pharmaceutical Co., Ltd. imagwiritsa ntchito njira yozindikira golide wa colloidal, yomwe imatha kuzindikira bwino mitundu yonse ya mitundu ya cryptococcal.Opaleshoniyo ndi yosavuta, ndipo zotsatira zake zimakhala zomveka komanso zothandiza.Pambuyo powona zotsatira za mayeso zitha kupezeka mumphindi 10!Perekani maziko odalirika pakuzindikiritsa koyambirira komanso kofulumira kwa Cryptococcus!
Gwero la Nkhani:
Shi D, Haas PJ, Boekhout T, et al.Kunyalanyaza kusiyanasiyana kwa majini kumalepheretsa kuzindikira kwanthawi yake matenda a Cryptococcus[J].Journal of Clinical Microbiology, 2021.
Ulalo wankhani:
https://journals.asm.org/doi/10.1128/JCM.02837-20
Nthawi yotumiza: Jul-28-2021