Carbapenem-resistant NDM Detection K-Set (Lateral Flow Assay) ndi njira yoyesera ya immunochromatographic yopangidwira kuzindikira kwamtundu wa NDM-mtundu wa carbapenemase m'magulu a bakiteriya.Kuyesaku ndi kuyesa kwa labotale yogwiritsira ntchito mankhwala komwe kungathandize kuzindikira mitundu ya NDM-mtundu wa carbapenem wosamva.
Dzina | Carbapenem-resistant NDM Detection K-Set (Lateral Flow Assay) |
Njira | Lateral Flow Assay |
Mtundu wachitsanzo | Matenda a tizilombo |
Kufotokozera | 25 mayeso / zida |
Nthawi yozindikira | 10-15 min |
Kuzindikira zinthu | Carbapenem-resistant Enterobacteriaceae (CRE) |
Mtundu wozindikira | NDM |
Kukhazikika | K-Set imakhala yokhazikika kwa zaka 2 pa 2 ° C-30 ° C |
Carbapenem-resistant Enterobacteriaceae (CRE) ndi mtundu wa mabakiteriya.Angayambitse matenda aakulu omwe angakhale ovuta kuchiza.CRE idapeza dzina lawo chifukwa amalimbana ndi carbapenems.Carbapenems ndi gulu lapamwamba la maantibayotiki.Anapangidwa m'zaka za m'ma 1980 kuti athandize kuchiza mabakiteriya omwe sakanatha kuchiritsidwa ndi maantibayotiki ena.Mankhwala opha tizilombo amagwiritsidwa ntchito kupha mitundu ina ya mabakiteriya.Pali mitundu yambiri yamankhwala awa.M’kupita kwa nthaŵi, mabakiteriya ena sangaphedwenso ndi iwo.Izi zimatchedwa antibiotic resistance.Kufalikira kwachangu kwa CRE kumayambitsidwa ndi kugwiritsa ntchito mankhwala osokoneza bongo komanso kusagwira bwino odwala a CRE.Ngati zinthu sizikuyendetsedwa bwino, zidzakhudza kwambiri chisamaliro chaumoyo wa anthu, zomwe zimapangitsa kuti chithandizo chamankhwala ndi kulamulira matenda zikhale zovuta kwambiri.
Njira zodziwika bwino zopewera kufalikira kwa CRE ndi:
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Zikuwonekeratu kuwona kufunikira kwa kuyesa koyambirira kwa CRE m'njira zonse pamwambapa.Kuwunika mwachangu komanso molondola ndikofunikira pakulemba koyambirira kwa mitundu ya CRE, chitsogozo chamankhwala, komanso kuwongolera kwamankhwala ndi thanzi la anthu.
Carbapenemase imatanthawuza mtundu wa β-lactamase womwe ungathe hydrolyze imipenem kapena meropenem, kuphatikizapo A, B, D mitundu itatu ya michere yomwe imayikidwa ndi Ambler molecular structure.Pakati pawo, Kalasi B ndi metallo-β-lactamases (MBLs), kuphatikizapo IMP, VIM ndi NDM, ndi zina, zomwe zimatchedwa metalloenzyme, zomwe zimapezeka makamaka mu Pseudomonas aeruginosa, Acinetobacteria ndi Enterobacteriaceae bacteria.Kuyambira pomwe idanenedwa koyamba ku India mu 2008, NDM (New Delhi metallo-beta-lactamase) yafalikira padziko lonse lapansi pamlingo wowopsa.Pakadali pano, NDM yawonekera m'maiko ambiri ku Europe, United States, Canada ndi Mexico ku North America, ndi mayiko aku Asia monga China, Japan, South Korea ndi Singapore.M'mayiko ngati India ndi Pakistan, NDM yadzetsa mliri, ndipo chiwerengero cha 38.5%.Kupanga mankhwala ozindikira matenda a carbapenemase ndikofunikira kwambiri pakulemba koyambirira kwa mitundu yosamva mankhwala, kuwongolera mankhwala, komanso kuwongolera kwamankhwala ndi thanzi la anthu.
Chitsanzo | Kufotokozera | Kodi katundu |
Chithunzi cha CPN-01 | 25 mayeso / zida | Chithunzi cha CPN-01 |