Aspergillus Galactomannan ELISA Detection Kit
Chiyambi cha Zamalonda
FungiXpert® Aspergillus Galactomannan ELISA Detection Kit ndi njira yoyezera immunosorbent yolumikizidwa ndi Enzyme pozindikira mtundu wa antigen ya Aspergillus galactomannan mu zitsanzo za seramu ya akulu ndi ana ndi zitsanzo zamadzimadzi a bronchoalveolar lavage (BAL).
Chiwopsezo cha Invasive Aspergillosis (IA) mwa odwala omwe alibe chitetezo chamthupi chikuchulukirachulukira chifukwa cha kugwiritsa ntchito mankhwala osokoneza bongo.IA ili ndi chiwopsezo chachikulu cha kufa chifukwa chosowa mawonetseredwe azachipatala komanso njira zowunikira zowunikira.Aspergillus fumigatus ndi amodzi mwa tizilombo toyambitsa matenda omwe amayambitsa matenda oopsa a aspergillus mwa odwala omwe ali ndi matenda a immunosuppressive, otsatiridwa ndi Aspergillus flavus, Aspergillus niger ndi Aspergillus terreus.
Makhalidwe
| Dzina | Aspergillus Galactomannan ELISA Detection Kit |
| Njira | ELISA |
| Mtundu wachitsanzo | Seramu, BAL madzimadzi |
| Kufotokozera | 96 mayeso / zida |
| Nthawi yozindikira | 2 h |
| Kuzindikira zinthu | Aspergillus spp. |
| Kukhazikika | Chidacho chimakhala chokhazikika kwa chaka chimodzi pa 2-8 ° C |
| Kuchepetsa kuzindikira malire | 0.5 ng/mL |
Mbiri
Invasive Aspergillosis (IA)
Amene ali pachiwopsezo
Odwala ndi neutropenia yaitali, kutsatira kumuika kapena molumikizana ndi aukali immunosuppressive regimens.
Zochitika zambiri
5% mpaka 20%, kutengera kuchuluka kwa odwala.
Kuchuluka kwa imfa
50% mpaka 80% chifukwa cha kuchulukirachulukira kwa matendawa (mwachitsanzo, masabata 1-2 kuyambira chiyambi mpaka imfa).
Zovuta kuzindikira
Ndizovuta kupeza umboni wa histopathological.Kukhudzidwa kwa chikhalidwe ndi kochepa.≈30% ya milandu imakhalabe yosazindikirika komanso yopanda chithandizo paimfa.
Galactomannan (GM) mayeso
- Antigen ya aspergillus yomwe imapezeka mu khoma la cell yomwe imatulutsidwa panthawi ya kukula kwa aspergillosis.
- Masiku 7 mpaka 14 zizindikiro zina za matenda zisanachitike.
Mfundo yofunika
Ubwino wake
- More Advance
Njira yodziwira m'mphepete mwa mayiko, kukhudzika kwakukulu komanso kutsimikizika - Zolondola Zambiri
Konzani ndondomeko ya ntchito.Chepetsani chiopsezo choipitsidwa panthawi yoyesera - Mofulumirirako
Kuzindikira kwa gawo limodzi, kuchepetsa kuchuluka kwa makulitsidwe ndi nthawi yotsuka
- More Economic
Gawani ma microplate, kupulumutsa mtengo - Malangizo
Yalimbikitsidwa ndi malangizo a IDSA a Aspergillosis 2016 ndi ESCMID-ECMM-ERS malangizo a Aspergillosis 2018
Zotsatira zachipatala
Kuzindikira msanga
- GM ndi masiku 5-8 kale kuposa zizindikiro zachipatala za aspergillosis (IA);
- GM ndi masiku 7.2 kale kuposa mkulu kusamvana CT scan;
- GM ndi masiku 12.5 pasadakhale kuyamba kwa epirical antifungal therapy.
Kuwunika kwamphamvu
- GM ndi yofanana ndi kuchuluka kwa bowa, zomwe zimatha kuwonetsa kuchuluka kwa matenda.
- Zomwe zili mu GM antigen zidachepa ndikugwiritsa ntchito mankhwala oletsa kutupa.
Maziko ofunikira azachipatala
- Chepetsani kugwiritsa ntchito epirical antifungal chithandizo.
- Kulumikizana kwakukulu pakati pa zotsatira ndi index ya GM ya khansa ya hematological.
Kuzindikira kwa United kwa mayeso a G ndi GM
- Kukhazikika kwapamwamba komanso mtengo wolosera wabwino
- Kukhudzika kwakukulu
Kuitanitsa Zambiri
| Chitsanzo | Kufotokozera | Kodi katundu |
| GMKT-01 | 96 mayeso / zida | FGM096-001 |
